Healthy Inspirations

Reading Signal Body More Early with Examination Homeostasis Model Assessment (HOMA)

Mon, 24 Nov 2025

Friend PRAMITA, maintaining metabolic health is key for a life that is quality. One of modern ways to understand the condition of body metabolism more deeply is through examination HOMA. Let us get to know this advanced method, starting from benefits until how to read it.

1. Main Benefit of Examination HOMA
The biggest benefit from examination HOMA is its ability as a system of early detection. Far before blood sugar levels show abnormalities, HOMA already can give a picture whether the body of Friend PRAMITA is starting to have difficulty in responding to the hormone insulin. By detecting this signal earlier, we have a golden opportunity to conduct lifestyle intervention, such as improving diet patterns and increasing physical activity, in order to prevent the development of more serious health problems in the future, especially prediabetes and diabetes mellitus type 2.

2. Getting to Know HOMA-IR and HOMA-B
Examination HOMA produces two important scores that assess two different aspects of the sugar metabolism system in the body:

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance): Consider insulin as a key that opens the "door" of the cell so sugar can enter and become energy. HOMA-IR measures how effective or sensitive the cell "door" is towards the insulin key. This score indicates the level of insulin resistance inside the body.

HOMA-B (Homeostatic Model Assessment of Beta-cell Function): If insulin is the key, then the Beta cell in the pancreas organ is the "factory" that produces that key. HOMA-B functions to measure how good the capacity and health of this insulin-making factory is in working.

3. Understanding the Results of HOMA-IR and HOMA-B
The results of examination HOMA will give a number that needs to be interpreted by a doctor. But in general, here is the guide:

Interpretation of HOMA-IR: The higher the HOMA-IR score, the higher also the level of insulin resistance. This can be a sign that the body's cells are starting to become "immune" to the work of insulin, so the pancreas must work extra hard. Generally, a score above 2 is considered as a marker of insulin resistance.

Interpretation of HOMA-B: This score ideally is at the number 100%, which indicates the function of the insulin "factory" is running optimally. A score that decreases significantly indicates a decline in the ability of the pancreas to produce insulin in sufficient amounts for the body's needs.

4. When is This Examination Recommended?
Examination HOMA is highly recommended for Friend PRAMITA who has one or more risk factors for metabolic disorders, such as:

Having excess body weight (obesity), especially with fat accumulation in the abdominal area.
Having a family history with diabetes mellitus disease.
A lifestyle of less movement (sedentary).
Known to have a condition of high blood pressure or abnormal blood fat levels (cholesterol, triglycerides).
Women with a history of Polycystic Ovary Syndrome (PCOS).

By understanding both HOMA scores, a doctor can give a more accurate recommendation to maintain the health of Friend PRAMITA.

Preparation for Examination:

Fasting for at least 8–10 hours before blood collection. Only plain water is allowed.
Avoid foods high in sugar or fat the night before the test.
Do not smoke or engage in strenuous exercise before the examination.
If you are taking certain medications (especially diabetes drugs), consult your doctor to determine whether they should be temporarily discontinued.

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