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EXAMINATION FOR LEUKEMIA
Thu, 14 Jul 2022
Leukemia is a malignancy that occurs in white blood cells. According to the American Centers for Disease Control and Prevention (CDC), the disease begins in the bone marrow and spreads to the bloodstream.
Complaints that are often felt in patients with leukemia include: fever, chills, flu-like symptoms, weakness, fatigue, and joint pain accompanied by reduced appetite, weight loss, swollen glands, signs of bleeding (such as nosebleeds, bruising, bleeding gums, etc.), and anemia (CDC).
Examinations carried out by doctors in diagnosing leukemia include anamnesis, the patient's medical history and physical examination.
For laboratory investigations, the necessary tests are: complete blood count, blood smear, and bone marrow biopsy.
Complete blood tests can show an increase or decrease in the number of white blood cells and other blood cells. While the blood smear, can show the presence or absence of leukemia cells in the blood. A bone marrow biopsy is also often done to confirm the diagnosis and look for chromosomal abnormalities. These tests can also show the type of leukemia cell (Leukemia and Lymphoma Society, 2012).
While radiological examinations, X-rays, ultrasonography (USG), CT scans, and MRI (Magnetic Resonance Imaging) can be performed to assist in establishing the diagnosis and monitoring the course of the disease (CDC).
Author: dr. Alamanda Prycilia (Medical Consultant Doctor of PRAMITA Clinical Laboratory Jl. Jemur Andayani No. 67 Surabaya)
REFERENCE
CDC. Questions and Answers about Leukemia. Taken from: https://www.cdc.gov/nceh/radiation/phase2/mleukemi.pdf
Tebbi, Cameron K. 2021. Etiology of Acute Leukemia: A Review. Cancers 2021, 13, 2256. Taken from: https://doi.org/10.3390/cancers13092256
Leukemia and Lymphoma Society. 2012. Understanding Leukemia. Taken from: https://www.lls.org/sites/default/files/file_assets/understandingleukemia.pdf
Complaints that are often felt in patients with leukemia include: fever, chills, flu-like symptoms, weakness, fatigue, and joint pain accompanied by reduced appetite, weight loss, swollen glands, signs of bleeding (such as nosebleeds, bruising, bleeding gums, etc.), and anemia (CDC).
Examinations carried out by doctors in diagnosing leukemia include anamnesis, the patient's medical history and physical examination.
For laboratory investigations, the necessary tests are: complete blood count, blood smear, and bone marrow biopsy.
Complete blood tests can show an increase or decrease in the number of white blood cells and other blood cells. While the blood smear, can show the presence or absence of leukemia cells in the blood. A bone marrow biopsy is also often done to confirm the diagnosis and look for chromosomal abnormalities. These tests can also show the type of leukemia cell (Leukemia and Lymphoma Society, 2012).
While radiological examinations, X-rays, ultrasonography (USG), CT scans, and MRI (Magnetic Resonance Imaging) can be performed to assist in establishing the diagnosis and monitoring the course of the disease (CDC).
Author: dr. Alamanda Prycilia (Medical Consultant Doctor of PRAMITA Clinical Laboratory Jl. Jemur Andayani No. 67 Surabaya)
REFERENCE
CDC. Questions and Answers about Leukemia. Taken from: https://www.cdc.gov/nceh/radiation/phase2/mleukemi.pdf
Tebbi, Cameron K. 2021. Etiology of Acute Leukemia: A Review. Cancers 2021, 13, 2256. Taken from: https://doi.org/10.3390/cancers13092256
Leukemia and Lymphoma Society. 2012. Understanding Leukemia. Taken from: https://www.lls.org/sites/default/files/file_assets/understandingleukemia.pdf
